Recognition of Azole-Resistant Aspergillosis by Physicians Specializing in Infectious Diseases, United States
نویسندگان
چکیده
Infections caused by pan-azole-resistant Aspergillus fumigatus strains have emerged in Europe and recently in the United States. Physicians specializing in infectious diseases reported observing pan-azole-resistant infections and low rates of susceptibility testing, suggesting the need for wider-scale testing.
منابع مشابه
Aspergillosis due to voriconazole highly resistant Aspergillus fumigatus and recovery of genetically related resistant isolates from domiciles.
BACKGROUND Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the management of patients with Aspergillus-related diseases. Selection of azole resistance may occur through exposure to azole fungicides in the environment. In the Netherlands a surveillance network was used to investigate the epidemiology of resistance selection in A. fumigatus. METHODS Clinical A. ...
متن کاملEfficacy and safety of posaconazole for chronic pulmonary aspergillosis: next strategy against the threat of azole-resistant Aspergillus infection
Right © 2010 by the Infectious Diseases Society of America; This is a pre-copyediting, author-produced PDF of an article accepted for publication in Clinical infectious diseases following peer review. The definitive publisher-authenticated version Clinical infectious diseases, 51(12), pp.1392-1394; 2010 is available online at: http://cid.oxfordjournals.org/content/51/12/1392.full. NAOSITE: Naga...
متن کاملAzole Resistance in Aspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?
Azole resistance in Aspergillus fumigatus has emerged as a global health problem. Although the number of cases of azole-resistant aspergillosis is still limited, resistance mechanisms continue to emerge, thereby threatening the role of the azole class in the management of diseases caused by Aspergillus. The majority of cases of azole-resistant disease are due to resistant A. fumigatus originati...
متن کاملProspective Multicenter International Surveillance of Azole Resistance in Aspergillus fumigatus
To investigate azole resistance in clinical Aspergillus isolates, we conducted prospective multicenter international surveillance. A total of 3,788 Aspergillus isolates were screened in 22 centers from 19 countries. Azole-resistant A. fumigatus was more frequently found (3.2% prevalence) than previously acknowledged, causing resistant invasive and noninvasive aspergillosis and severely compromi...
متن کاملClinical Implications of Azole Resistance in Aspergillus fumigatus, the Netherlands, 2007–2009
The prevalence and spread of azole resistance in clinical Aspergillus fumigatus isolates in the Netherlands are currently unknown. Therefore, we performed a prospective nationwide multicenter surveillance study to determine the effects of resistance on patient management strategies and public health. From June 2007 through January 2009, all clinical Aspergillus spp. isolates were screened for i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 24 شماره
صفحات -
تاریخ انتشار 2018